Butea superba Roxb. Enhances Penile Erection in Rats Source: Phytother Res. 2006; 20(6):484-9 (ISSN: 0951-418X) Tocharus C; Smitasiri Y; Jeenapongsa R Faculty of Pharmaceutical Sciences, Naresuan University, Phitsanulok 65000 Thailand. This study aimed to investigate the effects of ethanol extracts of Butea superba in increasing intracavernous pressure (ICP) in vivo. The extracts were prepared from fresh and dried root cores and fresh and dried root barks. Penile erection was induced in aged rats by electrical stimulation of the cavernous nerve. Cavernous smooth muscle relaxation was also observed in vitro in the presence of the extract, cGMP or isobutyl-methylxanthine (IBMX) alone or the extract together with cGMP or IBMX. The dried root core extract from Phrae was the most effective in increasing the ICP. The dose-response relationship study revealed a bell-shape curve with the maximum effective dose at 1 mg/kg. The ICP of the control and 1 mg/kg extract-treated animals were 45.3 +/- 2.5 and 100.9 +/- 14.0 mmHg, respectively. The extract, cGMP and IBMX alone induced dose dependent muscle relaxation. Butea superba significantly enhanced the effects of cGMP and IBMX. The results suggest that ethanol extracts of Butea superba are effective in enhancing penile erection. The dried root core extract from Phrae is the most effective part with a maximal dose of 1 mg/kg. The results also suggest that Butea superba may act through cAMP/cGMP pathways. Home page Sitemap Pueraria mirifica breast herb Curcuma comosa vaginal wall tightening herb Pure marine collagen for the neck skin Beauty tips Beauty glossary Young tips Skin care tips Detoxification Aging Health tips All about Green tea All about Weight loss Sleeping tips Tag: Butea superba, butea superba male oil, kwao krua dang, red kwao krua, natural male enhancement herbs, men's health, butea superba herb, herbal viagra | 
